Family Physicians Called On to Administer Monoclonal Antibody Treatment

May 27, 2021—With monoclonal antibody therapy proven to significantly help reduce COVID-19 symptoms and risk of hospitalization and death, Gov. Gretchen Whitmer and Michigan Department of Health and Human Services are calling on physicians to expand the number of infusion sites in the state.

There are already many sites providing monoclonal antibody therapy (mAb) in at least 37 Michigan counties. The goal is for 50% of eligible high-risk Michiganders who test positive for COVID-19 to receive the therapy within 10 days of symptom onset.

Monoclonal antibodies are laboratory-produced molecules that can restore, enhance, or mimic the immune system's attack on cells. mAb targets different parts of the virus and prevents it from bonding with cells in the body, effectively neutralizing it. 

How to Become an mAb Provider

In addition to infusion centers and hospitals, mAb may be delivered in primary care practices provided that qualified medical personnel are onsite to infuse and monitor patients and are able to respond to allergic reactions. Urgent care centers, surgical centers, dialysis centers, federally qualified health centers, and home healthcare organizations may also consider operationalizing to offer mAb therapy.

If your practice would like to offer infusions, you may order mAb directly from Amerisource Bergen Corporation (ABC), the sole distributor of the drug. There is no shortage of supply. Click here for the direct ordering process guide. Click here for ABC’s direct order request form.

Coding & Billing

Monoclonal antibody therapies remain free of charge for requesting sites, and treatment is available with no out-of-pocket costs for patients. Infusion administration charges are reimbursable through Medicare, Medicaid, and most third-party insurers. CPT codes will be issued for reimbursement. CMS has released billing and payment guidance for Medicare beneficiaries.

Locating Infusion Sites

If your practice is not an infusion site and you would like to refer patients to the nearest location for receiving mAb treatment, call the mAb therapy call center at 1.877.366.0310 or visit

Click here for more resources on COVID-19 monoclonal antibody therapy.